Definitions:

1. A congenital sexual disorder that prevents the testicles from maturing at puberty. NOUN
   • Kallmann's syndrome is caused by mutations in genes that are involved in the development of the hypothalamus and pituitary gland.
2. A rare genetic disorder characterized by a hypogonadotropic hypogonadism, a condition where the body produces insufficient sex hormones, and insomnia. NOUN
   • Hormone replacement therapy is the standard treatment for individuals with Kallmann's syndrome to help induce puberty and manage other symptoms.
3. A rare genetic disorder characterized by delayed or absent puberty and an impaired or absent sense of smell. NOUN
   • The patient was diagnosed with Kallmann's syndrome after presenting with delayed puberty and an inability to smell.

Synonyms:

• delayed puberty
• ganadotropin deficiency
• reproductive disorder